Nemabiome metabarcoding reveals differences between gastrointestinal nematode species infecting co-grazed sheep and goats

Our current understanding of differences in the epidemiology gastrointestinal nematode (GIN) species co-grazed sheep and goats is inadequate with reference to development sustainable control strategies. The next-generation metabarcoding sequencing method referred as ‘nemabiome’ allows some these be explored describe intensity co-infecting GIN species. We applied this platform study that were on Guinea grass pasture northeastern Brazil. Co-grazed treated a monepantel anthelmintic, then exposed same Overall, there prevalence identified goats; Trichostrongylus colubriformis Teladorsagia circumcincta predominated goat kids, while Haemonchus contortus adult does, ewes lambs once burdens became re-established after anthelmintic treatment. Description pattern re-infection following treatment was prevented by unpredicted poor efficacy 2.5 mg/kg 5 mg/kg, respectively, against O. columbianum T. lambs, does. Differences drug between host age groups may important when considering strategies for animals. aggregated FECs does kids representing burdens, higher than those lambs. This implies are inherent adaptation two naïve small ruminant species, shows need better factors giving rise situation associated exposure infective larvae responses. At start study, co-infected several highest circumcincta, contrasting ewes, which H. predominated. However, treatment, both ewes. demonstrates potential establish predominate low.